| Details |
| Disease Name | Pituitary Neoplasms |
| Nocoding RNA Name | hsa-miR-185 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | qRT-PCR,Luciferase Reporter Assay etc. |
| Target | SSTR2 |
| Tissue | brain(pituitary tissues) |
| Treatment | Long-acting somatostatin analogs(SSAs) |
| PubMed ID | 26036598 |
| Year | 2015 |
| Detail Description | The expression level of miR-185 was 5.85 ± 1.92 in the non-responder group, 0.37 ± 0.07 in the responder group, and 2.48 ± 1.00 in the normal pituitary gland group. These results confirmed our finding in the miRCURY LNA arrays that miR-185 was upregulated in SSA non-responders.using Dual Luciferase reporter assay demonstrated that miR-185 likely targets the 3′-UTR of SSTR2 mRNA in the rat pituitary adenoma GH3 cell line. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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