We have applied miRNA-microarrays to identify deregulated miRNA candidates in brainsof BSE-infected macaques. Shock-frozen brain sections of six BSE-infected and five non-infected macaques were used to validate regulated miRNA candidates by two independent qRT-PCR-based methods. Our study revealed significant upregulation of hsa-miR-342-3p and hsa-miR-494 in the brains ofBSE-infected macaques compared to non-infected animals.
NSDNA: The Nervous System Disease NcRNAome Atlas
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