| Disease Name |
Huntington Disease |
| Nocoding RNA Name |
hsa-miR-196a-5p |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
next-generation miRNA sequencing,RT-qPCR etc. |
| Target |
N/A |
| Tissue |
brain(cortex) |
| Treatment |
N/A
|
| PubMed ID |
24586208 |
| Year |
2014 |
| Detail Description |
Using next-generation miRNA sequencing in prefrontal cortex(Brodmann Area 9) of twelve HD and nine controls, we identified five miRNAs (miR-10b-5p, miR-196a-5p, miR-196b-5p, miR-615-3p and miR-1247-5p) up-regulated in HD at genome-wide significance,Expression was verified for all five miRNAs using reverse transcription quantitative PCR and all but miR-1247-5p were replicated in an independent sample. |
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