| Disease Name |
Medulloblastoma |
| Nocoding RNA Name |
hsa-miR-199b-5p |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
qRT-PCR,Western Blot,Chromatin immunoprecipitation,Flow Cytometry etc. |
| Target |
N/A |
| Tissue |
medulloblastoma cell lines |
| Treatment |
DAPT(a g-secretase complex inhibitor)
|
| PubMed ID |
22411914 |
| Year |
2012 |
| Detail Description |
we analyzed miR-199b-5p expression within these assays using miRNA TaqMan assay, which demonstrated that after DAPT treatment and Hes1 downregulation,miR-199b-5p expression increased gradually, with significant upregulation 12 h after treatment.miR-199b-5p binds the 3′-UTR of CD15 mRNA, thus impairing its expression. |
|