Details
Disease Name Medulloblastoma
Nocoding RNA Name hsa-miR-199b-5p
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR,Western Blot,Chromatin immunoprecipitation,Flow Cytometry etc.
Target N/A
Tissue medulloblastoma cell lines
Treatment DAPT(a g-secretase complex inhibitor)
PubMed ID 22411914
Year 2012
Detail Description we analyzed miR-199b-5p expression within these assays using miRNA TaqMan assay, which demonstrated that after DAPT treatment and Hes1 downregulation,miR-199b-5p expression increased gradually, with significant upregulation 12 h after treatment.miR-199b-5p binds the 3′-UTR of CD15 mRNA, thus impairing its expression.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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