Details
Disease Name Meningioma
Nocoding RNA Name hsa-miR-200a
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods microarray, qRT-PCR, Luciferase Reporter Assay etc.
Target β-catenin
Tissue brain(meningioma tissue)
Treatment N/A
PubMed ID 19703993
Year 2009
Detail Description A direct correlation was found between the downregulation of miR-200a and the upregulation of β-catenin in human meningioma samples. Thus, miR-200a appears to act as a multifunctional tumor suppressor miRNA in meningiomas through effects on the E-cadherin and Wnt/β-catenin signaling pathways.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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