| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-200a |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Quantitative Real-time PCR,Cell transfection etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | temozolomide |
| PubMed ID | 24755707 |
| Year | 2014 |
| Detail Description | miR21 is upregulated in grade IV (glioblastoma multiforme (GBM)) vs. grade II-III (LGs) gliomas, confirming that miR21 expression level is correlated with tumor grade, and that it may be considered as a marker of tumor progression. conversely, miR200a is demonstrated for the first time to be downregulated in GBMs compared with LGs, and overexpression of miR200a in GBM cells is shown to promote TMZ-sensitivity. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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