Details
Disease Name Astrocytoma
Nocoding RNA Name hsa-miR-200b
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods qRT-PCR etc.
Target N/A
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 25033730
Year 2014
Detail Description Both miR-200b and CREB-1 messenger RNA expression was measured in 122 astrocytomas and 30 nonneoplastic brain specimens by quantitative real-time polymerase chain reaction. Expression of miR-200b was significantly lower in astrocytoma than in nonneoplastic brain (P < .001), whereas CREB-1 messenger RNA expression was significantly elevated in the tumors (P < .001). Both miR-200b down-regulation and CREB-1 up-regulation were significantly associated with advanced pathologic grade (P = .002 and P = .006, respectively).

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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