Details
Disease Name Glioma
Nocoding RNA Name hsa-miR-203
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods RT-PCR,Luciferase Reporter Assay etc.
Target PLD2
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 24270883
Year 2014
Detail Description Real-time reverse transcription polymerase chain reaction (RT-PCR) showed that the expression of miR-203 in high WHO grade glioma tissues was significantly decreased compared with low WHO grade glioma tissues and normal brain tissues, and its expression demonstrated a decreasing tendency with ascending WHO grades. The transfection of the miR-203 mimic into U251 cells markedly downregulated the expression of phospholipase D2 (PLD2), which was identified as a direct target of miR-203.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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