| Details |
| Disease Name | Epilepsy, Temporal Lobe |
| Nocoding RNA Name | hsa-miR-204 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | miRNA microarray,qRT-PCR,Dual Luciferase Reporter Assay etc. |
| Target | GRM1 |
| Tissue | brain(hippocampus) |
| Treatment | N/A |
| PubMed ID | 25410734 |
| Year | 2014 |
| Detail Description | miRNA array expression profiling of hippocampus biopsies from 10 Danish HS patients revealed 30 differentially expressed miRNAs (significance analysis of microarray (SAM), false discovery rate 20, delta 0.42), where 25 miRNAs were up-regulated and 5 were down-regulated compared to non-HS surgical specimens.we identified four target genes, involved in axonal guidance and synaptic plasticity, ROBO1, GRM1, SLC1A2, and GNAI2, as bona fide targets of miR-218. GRM1 was also shown to be a direct target of miR-204. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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