| Disease Name |
Myotonic Dystrophy |
| Nocoding RNA Name |
hsa-miR-206 |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
qRT-PCR, Northern Blot, Western Blot, in situ hybridization etc. |
| Target |
N/A |
| Tissue |
muscle(skeletal muscle) |
| Treatment |
N/A
|
| PubMed ID |
20487562 |
| Year |
2010 |
| Detail Description |
Only miR-206 showed an over-expression in 5 of 7 DM1 patients (threshold = 2, fold change between 1.20 and 13.22, average = 5.37) compared to the control group. This result has been further confirmed by Northern blot analysis (3.37-fold overexpression, R2 = 0.89). In situ hybridization localized miR-206 to nuclear site both in normal and DM1 tissues. |
|