Details
Disease Name Myotonic Dystrophy
Nocoding RNA Name hsa-miR-206
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR, Northern Blot, Western Blot, in situ hybridization etc.
Target N/A
Tissue muscle(skeletal muscle)
Treatment N/A
PubMed ID 20487562
Year 2010
Detail Description Only miR-206 showed an over-expression in 5 of 7 DM1 patients (threshold = 2, fold change between 1.20 and 13.22, average = 5.37) compared to the control group. This result has been further confirmed by Northern blot analysis (3.37-fold overexpression, R2 = 0.89). In situ hybridization localized miR-206 to nuclear site both in normal and DM1 tissues.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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