Our data show that miR-21 and SOX2 are tightly regulated already during embryogenesis and define a distinct population with putative tumor cell of origin characteristics.Furthermore,we believe that miR-21 is a mediator of PDGF-driven brain tumors,which suggests miR-21 as a promising target for treatment of glioma.
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback