| Disease Name |
Astrocytoma |
| Nocoding RNA Name |
hsa-miR-21 |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
Real-time PCR,Northern Blot etc. |
| Target |
N/A |
| Tissue |
brain(brain tumor tissue) |
| Treatment |
N/A
|
| PubMed ID |
19159078 |
| Year |
2009 |
| Detail Description |
Expression of miR-21, 221, 128a, 128b, 128c, 181a, 181b, 181c was studied using real-time quantitative reverse transcriptase polymerase chain reaction and northern blotting for human astrocytic tumors with different grade of malignancy. miR-21 and 221 were overexpressed in glioma samples, whereas miRNA 181b was downregulated compared with normal brain tissue. miRNA-21 was hyperexpressed in all tumor samples whereas higher levels of miRNA-221 were found in high-grade gliomas. |
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