Details
Disease Name Astrocytoma
Nocoding RNA Name hsa-miR-21
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time PCR,Northern Blot etc.
Target N/A
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 19159078
Year 2009
Detail Description Expression of miR-21, 221, 128a, 128b, 128c, 181a, 181b, 181c was studied using real-time quantitative reverse transcriptase polymerase chain reaction and northern blotting for human astrocytic tumors with different grade of malignancy. miR-21 and 221 were overexpressed in glioma samples, whereas miRNA 181b was downregulated compared with normal brain tissue. miRNA-21 was hyperexpressed in all tumor samples whereas higher levels of miRNA-221 were found in high-grade gliomas.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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