Details
Disease Name Medulloblastoma
Nocoding RNA Name hsa-miR-21
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR etc.
Target N/A
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 21775132
Year 2011
Detail Description To assess the relevance of miR-21 in MB biology we first determined its expression level comparing to normal brain tissue in 29 MB patient’s samples as well as in a representative panel of 6 MB cell lines using quantitative reverse transcriptasepolymerase chain reaction (qRT-PCR). Interestingly, compared with normal human cerebellum, miR-21 expression was found to be up-regulated in every MB sample and MB cell line tested, with its level between 10- to 130-fold higher in MB cell nucleotide referred to as scrambled.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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