Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-21
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods qRT-PCR, Cell Culture,transfection etc.
Target N/A
Tissue glioblastoma cell lines U251 and LN229
Treatment taxol
PubMed ID 20113523
Year 2010
Detail Description Transfection of the miR-21 inhibitor altered mir-21 levels relative to the control by 9.4-fold and 8.5-fold in U251 and LN229 glioblastoma cells, respectively. Interestingly, taxol alone also downregulated miR-21 expression. In both LN229 and U251 glioblastoma cells, the lowest level of miR-21 expression was achieved by treatment with the miR-21 inhibitor in combination with taxol therapy.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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