Elevated levels of mir-21 were observed in all 7 glioblastoma-derived cell lines and in all 13 glioblastoma tumors we examined.We demonstrate that downregulation of mir-21 in glioblastoma-derived cell lines results in increased expression of its target, programmed cell death 4(Pdcd4), a known tumor-suppressor gene.
NSDNA: The Nervous System Disease NcRNAome Atlas
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