Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-21
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time PCR,Western Blot,Northern Blot etc.
Target Pdcd4
Tissue glioblastoma cell lines
Treatment N/A
PubMed ID 21636706
Year 2011
Detail Description Elevated levels of mir-21 were observed in all 7 glioblastoma-derived cell lines and in all 13 glioblastoma tumors we examined.We demonstrate that downregulation of mir-21 in glioblastoma-derived cell lines results in increased expression of its target, programmed cell death 4(Pdcd4), a known tumor-suppressor gene.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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