Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-21
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time RT-PCR,Transfections,Western Blot etc.
Target N/A
Tissue glioblastoma cell lines(U251)
Treatment ionizing radiation(IR)
PubMed ID 21618027
Year 2011
Detail Description miR-21 expression was upregulated in response to ionizing radiation (IR) in U251 cells, which suggested that miR-21 could be involved in the response of U251 cells to radiation. We showed that a miR-21 inhibitor enhanced IR-induced glioblastoma cell growth arrest and increased the level of apoptosis, which was probably caused by abrogation of the G2-M arrest induced by IR.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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