| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-21 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Cell culture,transfection,Western Blot,Quantitative Real-time PCR etc. |
| Target | N/A |
| Tissue | glioblastoma cell lines |
| Treatment | N/A |
| PubMed ID | 22907752 |
| Year | 2012 |
| Detail Description | hnRNPC bound directly to primary miR-21 (pri-miR-21) and promoted miR-21 expression in T98G cells.Silencing of hnRNPC lowered miR-21 levels, in turn increasing the expression of PDCD4, suppressing Akt and p70S6K activation, and inhibiting migratory and invasive activities. Silencing of hnRNPC reduced cell proliferation and enhanced etoposideinduced apoptosis. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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