Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-21
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time PCR,Plasmids,Oligonucleotides,Cell Transfection etc.
Target hMSH2
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 23904372
Year 2013
Detail Description Real-time PCR showed that the expression level of miR-21 was much higher in the three glioblastoma cell lines than in normal brain tissue.In the six glioblastoma patients, the relative expression level of miR-21 was obviously increased in the radio-resistant group when compared with the radio-sensitive group.miR-21 may mediate the resistance of glioblastoma cells against radiation via its target genes PDCD4 and hMSH2.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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