| Disease Name |
Frontotemporal Dementia |
| Nocoding RNA Name |
hsa-miR-212 |
| Expression Pattern |
down-regulated |
| Species |
Homo sapiens |
| Detection Methods |
microarray, qRT-PCR, immunofluorescence, immunoblotting, ELISA etc. |
| Target |
TMEM106B |
| Tissue |
brain(frontal cortex) |
| Treatment |
N/A
|
| PubMed ID |
22895706 |
| Year |
2012 |
| Detail Description |
Thus, TMEM106B is an FTLD-TDP risk gene, with microRNA-132/212 depression as an event which can lead to aberrant overexpression of TMEM106B, which in turn alters progranulin pathways. |
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