Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-218
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods NanoString assay etc.
Target N/A
Tissue glioblastoma cell lines
Treatment N/A
PubMed ID 22431589
Year 2012
Detail Description the predominant consequence of p53 induction in this model system was widespread repression of miRNAs expression (17 p53-repressed miRNAs of 31 total p53 responsive miRNAs;P<0.05).stem loop quantitative RT-PCR (qRT-PCR) analysis in cells with activated p53; miR-25 and -32 were significantly down-regulated on treatment with Nutlin-3a in p53-activated U87 cells, whereas miR-34a, a direct target of p53, was up-regulated.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

Contact wanglh211@163.com for inquiries and feedback

© All right reserved 2016