| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-218 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Quantitative RT-PCR,Western Blot etc. |
| Target | PLCγ1 |
| Tissue | brain(brain tumor tissue) |
| Treatment | temozolomide |
| PubMed ID | 24368849 |
| Year | 2014 |
| Detail Description | expression of microRNA-218(miR-218) is decreased significantly in highly necrotic mesenchymal GBM, and orthotopic tumor studies revealed that reduced miR-218 levels confer GBM resistance to chemotherapy. Importantly,miR-218 targets multiple components of receptor tyrosine kinase (RTK) signaling pathways, and miR-218 repression increases the abundance and activity of multiple RTK effectors. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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