| Details |
| Disease Name | Astrocytoma |
| Nocoding RNA Name | hsa-miR-219-5p |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | microarray etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 23690991 |
| Year | 2013 |
| Detail Description | In the miRNA microarray data, the expression of miR-219-5p was found to be significantly downregulated (p = 0.0024) in anaplastic astrocytoma (n = 13) by 3-fold as well as in glioblastoma(n = 26) by 5-fold when compared to the control normal brain tissue (n = 7). We further validated the downregulation of miR-219-5p by real-time qPCR in an independent cohort of glioblastoma patient samples. In the validation set, miR-219-5p expression was significantly downregulated (p = 0.0098) in glioblastoma patient samples (n = 24) by 12-fold (median log 2 ratio of 23.6) when compared to the control normal brain tissue (n = 3). |
NSDNA: The Nervous System Disease NcRNAome Atlas
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