Details
Disease Name Pituitary Neoplasms
Nocoding RNA Name hsa-miR-22*
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods qRT-PCR etc.
Target N/A
Tissue brain(pituitary tissues)
Treatment bromocriptine
PubMed ID 25064468
Year 2014
Detail Description 12 of these were validated by stem-loop qRT-PCR. Hsa-mir-93, hsa-mir-17, hsa-mir-22*, hsa-mir-126*, hsa-mir-142-3p, hsa-mir-144*, hsa-mir-486-5p, hsa-mir-451, and hsa-mir-92a were up-regulated and hsa-mir-30a, hsa-mir-382, and hsa-mir-136 were down-regulated in bromocriptine-resistant prolactinomas in comparison with bromocriptine-sensitive prolactinomas.Mir-93 directly affected p21 expression in MMQ cells by targeting the 3′-UTR.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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