Details
Disease Name Glioma
Nocoding RNA Name hsa-miR-221
Expression Pattern mutated
Species Homo sapiens
Detection Methods Northern Blot,Western Blot,Luciferase Reporter Assay etc.
Target p27Kip1
Tissue cell lines(human glioblastoma cells)
Treatment N/A
PubMed ID 19424584
Year 2009
Detail Description Our results suggest that miR-221/222 is a regulator of the tumor suppressor gene p27Kip1,and co-suppression of miR-221/222 expression in advanced gliomas may inhibit glioma cell proliferation by a mechanism involving the up-regulation of p27Kip1 in vitro and in vivo.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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