Details
Disease Name Carotid Stenosis
Nocoding RNA Name hsa-miR-222
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods RT-qPCR etc.
Target N/A
Tissue plaque
Treatment N/A
PubMed ID 26451018
Year 2015
Detail Description The urgent group exhibited a significant decrease in miR-221 and miR-222 expression in the plaque shoulder, whereas no significant differences were seen in miR-145 across the 3 groups. Regression analysis demonstrated a significant correlation between time from the neurological event to CEA and increasing miR-221 and miR-222, but not miR-145. mRNA encoding p27(Kip1), a target of miR-221 and miR-222 that inhibits vascular smooth muscle cell proliferation, was increased in the urgent group.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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