Details
Disease Name Alzheimer Disease
Nocoding RNA Name hsa-miR-23b
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods microarray etc.
Target N/A
Tissue brain
Treatment N/A
PubMed ID 18234899
Year 2008
Detail Description BACE1 mRNA levels tended to increase as miR-107 levels decreased in the progression of AD.Cell culture reporter assays performed with a subset of the predicted miR-107 binding sites indicate the presence of at least one physiological miR-108 miRNA recognion sequence in the 3-UTR of BACE1 mRNA.MiR-107 may be involved in accelerated disease progression through regulation of BACE1.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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