| Details |
| Disease Name | Multiple Sclerosis, Relapsing-Remitting |
| Nocoding RNA Name | hsa-miR-26a |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Quantitative Real-time PCR,Western Blot,Luciferase Reporter Assay etc. |
| Target | IL6 |
| Tissue | blood(lymphocytes) |
| Treatment | N/A |
| PubMed ID | 25362566 |
| Year | 2015 |
| Detail Description | In clinical samples of RRMS patients, it was found that miR26a expression was significantly lower in peripheral blood lymphocytes (PBLs) of patients with RRMS.an IL6-associated miRNA, miR26a, was identified, and its normally downregulated expression was shown to be highly correlated with disease severity in patients suffering from MS as well as in C57BL/6 mice with experimental autoimmune encephalomyelitis (EAE; a well-established animal model of human MS). miR26a was found to downregulate Th17 and to upregulate Treg cell function through its targeting of IL6. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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