| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-297 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Real-time PCR,Luciferase Reporter Assay etc. |
| Target | DGK-a |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 24158111 |
| Year | 2013 |
| Detail Description | we measured the levels of this microRNA in glioblastoma patient samples and compared it with normal brain samples using qPCR, whose measurements revealed lower levels of miR-297 in the patient samples versus normal brain.miR-297 as a highly cytotoxic microRNA in glioblastoma, with minimal cytotoxicity to normal astrocytes. miR-297 overexpression reduced in vitro invasiveness and in vivo tumor formation. DGK-a is shown to be a miR-297 target with a critical role in miR-297 toxicity. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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