| Details |
| Disease Name | Sarcopenia |
| Nocoding RNA Name | hsa-miR-29a |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | miRNA array, qPCR, Luciferase Reporter Assay etc. |
| Target | IGF-1 |
| Tissue | muscle |
| Treatment | N/A |
| PubMed ID | 24659628 |
| Year | 2014 |
| Detail Description | The mechanisms underlying the development of aging-induced muscle atrophy are unclear. By microRNA array and individual qPCR analyses, we found significant up-regulation of miR-29 in muscles of aged rodents vs. results in young. With aging, p85α, IGF-1 and B-myb muscle levels were lower while the expression of certain cell arrest proteins (p53, p16 and pRB) increased. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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