Details
Disease Name Amyotrophic Lateral Sclerosis
Nocoding RNA Name hsa-miR-29b
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Real-time qPCR etc.
Target PGC-1α
Tissue muscle
Treatment N/A
PubMed ID 22975021
Year 2013
Detail Description Compared to healthy controls, miRNA 23a, 29b, 206 and 455 were increased inskeletal muscle of ALS patients. miR-23a repressed PGC-1α translationina3′UTR dependent manner. Transgenic mice over expressing miR-23a had a reduction in PGC-1alpha, cytochome-b and COXIV protein levels.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

Contact wanglh211@163.com for inquiries and feedback

© All right reserved 2016