| Disease Name |
Glioblastoma |
| Nocoding RNA Name |
hsa-miR-29b |
| Expression Pattern |
down-regulated |
| Species |
Homo sapiens |
| Detection Methods |
qRT-PCR,Luciferase Reporter Assay and Vector Construction etc. |
| Target |
PDPN |
| Tissue |
brain(brain tumor tissue) |
| Treatment |
N/A
|
| PubMed ID |
20665731 |
| Year |
2010 |
| Detail Description |
we focused onmiR-29b and miR-125a, which were predicted to regulate PDPN, and demonstrated that these microRNAs directly target the 3-untranslated region of PDPN and inhibit invasion, apoptosis, and proliferation of glioblastomas. Furthermore, we report that miR-29b and miR-125a are downregulated in glioblastomas and also in CD133-positive cells. |
|