Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-29b
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods qRT-PCR,Luciferase Reporter Assay and Vector Construction etc.
Target PDPN
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 20665731
Year 2010
Detail Description we focused onmiR-29b and miR-125a, which were predicted to regulate PDPN, and demonstrated that these microRNAs directly target the 3-untranslated region of PDPN and inhibit invasion, apoptosis, and proliferation of glioblastomas. Furthermore, we report that miR-29b and miR-125a are downregulated in glioblastomas and also in CD133-positive cells.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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