| Disease Name |
Seizures |
| Nocoding RNA Name |
hsa-miR-30b-5p |
| Expression Pattern |
down-regulated |
| Species |
Homo sapiens |
| Detection Methods |
genome-wide sequencing,qRT-PCR etc. |
| Target |
N/A |
| Tissue |
serum |
| Treatment |
N/A
|
| PubMed ID |
25984652 |
| Year |
2015 |
| Detail Description |
we found that 12 miRNAs were downregulated (miR-194-5p, -204-5p, -221-5p, -301a-3p, -30b-5p, -342-5p, -3605-5p, -4446-3p, -598-3p, -874-3p, -889-3p and novel-mir-451) and 3 were upregulated (miR-574-5p, novel-mir-67 and novel-mir-9) in drug-resistant group compared to drug-responsive group.The expression levels of the 15 miRNAs selected by high-throughput sequencing were determined using qRT-PCR in a cohort of 30 drug-resistant patients and 30 drug-responsive patients.As a result, miR-194-5p, -301a-3p, -30b-5p, -342-5p and -4446-3p were significantly decreased in drug-resistant patients when compared with drug-responsive patients; while novel-mir-67 was increased in drug-resistant patients. |
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