| Details |
| Disease Name | Medulloblastoma |
| Nocoding RNA Name | hsa-miR-31 |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Quantitative RT-PCR,Luciferase Reporter Assay etc. |
| Target | MCM2 |
| Tissue | medulloblastoma cell lines |
| Treatment | N/A |
| PubMed ID | 24970811 |
| Year | 2014 |
| Detail Description | down-regulation of miR-31 is a general phenomenon associated with tumorigenesis, we examined miR-31 expression in two established lines of human medulloblastoma cells DAOY and D283,expression of miR-31 was completely abolished in the rest group, suggesting that miR-31 might impose a hindrance to cell growth that must be overridden during tumorigenesis.When attached to the end of a luciferase reporter, the MCM2 3’-UTR repressed the luciferase activity in the P-miR-31 DAOY cells.Thus, MCM2 is a direct target of miR-31. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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