Details
Disease Name Chorea
Nocoding RNA Name hsa-miR-3139
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods next-generation miRNA sequencing etc.
Target N/A
Tissue brain(prefrontal cortex)
Treatment N/A
PubMed ID 25889241
Year 2015
Detail Description These results demonstrate that miRNA expression in cortical BA9 provides insight into striatal involvement and support a role for these miRNAs, particularly miR-10b-5p, in HD pathogenicity. The miRNAs identified in our studies of postmortem brain tissue may be detectable in peripheral fluids and thus warrant consideration as accessible biomarkers for disease stage, rate of progression, and other important clinical characteristics of HD.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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