| Details |
| Disease Name | Medulloblastoma |
| Nocoding RNA Name | hsa-miR-33b |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | Cell culture, transfection, transduction, Molecular cloning and assays etc. |
| Target | MYC |
| Tissue | medulloblastoma cell lines |
| Treatment | Lovastatin |
| PubMed ID | 22887866 |
| Year | 2012 |
| Detail Description | We used reporter assays to screen miRNAs for their ability to modulate c-Myc function and to target the MYC 3-UTR directly.We first employed D283 Med (D283), a medulloblastoma cell line without 17p11.2 and with high levels of c-Myc, but without MYC gene amplification.cells proliferated at a slower rate with miR-33b overexpression as determined by the MTT assay.lovastatin activates miR-33b through the cholesterol biosynthetic pathway. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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