NSDNA: The Nervous System Disease NcRNAome Atlas

Details

Disease Name	Medulloblastoma
Nocoding RNA Name	hsa-miR-34a
Expression Pattern	up-regulated
Species	Homo sapiens
Detection Methods	Real-time PCR,Luciferase Reporter Assay etc.
Target	Dll1
Tissue	medulloblastoma cell lines
Treatment	N/A
PubMed ID	21931765
Year	2011
Detail Description	As observed in other cell lines, our data show that endogenous miR-34a up-regulation by doxorubicin negatively influences the expression of Dll1, and this confirms our previous data using transient miR-34a regulation.in Daoy MB cells, Dll1 is the first target that is regulated in MB, as compared to the other targets analyzed here: Cyclin D1, cMyc and CDK4.

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