| Details |
| Disease Name | Chorea |
| Nocoding RNA Name | hsa-miR-34b |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | microarray, Real-time PCR etc. |
| Target | N/A |
| Tissue | serum |
| Treatment | N/A |
| PubMed ID | 21421997 |
| Year | 2011 |
| Detail Description | We then examined their presence and bio-stability in control and HD plasma. We found that miR-34b is significantly elevated in response to mHTT-Exon-1, and its blockade alters the toxicity of mHTT-Exon-1 in vitro.We also show that miR-34b is detectable in plasma from small input volumes and is insensitive to freeze-thaw-induced RNA degradation. Interestingly, miR-34b is significantly elevated in plasma from HD gene carriers prior to symptom onset. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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