| Disease Name |
Machado-Joseph Disease |
| Nocoding RNA Name |
hsa-miR-34b |
| Expression Pattern |
up-regulated |
| Species |
Homo sapiens |
| Detection Methods |
microarray,qRT-PCR etc. |
| Target |
N/A |
| Tissue |
serum |
| Treatment |
N/A
|
| PubMed ID |
23879331 |
| Year |
2014 |
| Detail Description |
the expression levels of 20 miRNAs were increased, whereas the levels of 26 miRNAs were decreased in the SCA3/MJD patients (fold change>2.0).To validate the microarray data, qRT-PCR was performed to detect the expression levels of four miRNAs from 35 patients and 25 controls. the expression level of miR-34b was significantly elevated, whereas the levels of miR-29a, miR-25, and miR-125b were downregulated in SCA3/MJD samples. |
|