| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-363 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | microarray,qPCR etc. |
| Target | Caspase 9 |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 24805821 |
| Year | 2014 |
| Detail Description | Using FACS sorting of low-passage cell samples followed by microRNA microarray analysis, we found 43 microRNAs that were dys-regulated in common in three separate CD133+human glioblastomas compared to CD133+normal neural stem cells.we next measured miR-582-5p and miR-363 via qPCR in many GBM and three normal human tissue specimens. We found that miR-582-5p was increased in six GBMs, up to ten fold relative to the normal samples.miR-363 was increased, sometimes to extremely high levels, in nine human specimens as compared to three averaged normal brain samples. miR-582-5p and miR-363 are shown to directly target Caspase 3, Caspase 9, and Bim. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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