NSDNA: The Nervous System Disease NcRNAome Atlas

Details

Disease Name	Medulloblastoma
Nocoding RNA Name	hsa-miR-367
Expression Pattern	detectable
Species	Homo sapiens
Detection Methods	Real-time PCR,Immunofluorescence,Cell cycle analysis etc.
Target	N/A
Tissue	human medulloblastoma cell lines
Treatment	N/A
PubMed ID	26250335
Year	2015
Detail Description	Basal expression of primary and mature forms of miR-367 were detected in four human medulloblastoma cell lines and expression of the latter was found to be upregulated upon enforced expression of OCT4A. Transient overexpression of miR-367 significantly enhanced tumor features typically correlated with poor prognosis; namely, cell proliferation, 3-D tumor spheroid cell invasion and the ability to generate neurosphere-like structures enriched in CD133 expressing cells.

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