Details
Disease Name Medulloblastoma
Nocoding RNA Name hsa-miR-422a
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods microarray etc.
Target N/A
Tissue medulloblastoma cell lines
Treatment N/A
PubMed ID 20574517
Year 2010
Detail Description list of statistically significant human microRNAs with decreased expression in all three medulloblastoma samples to 30 microRNAs.We next performed real time RT-PCR on a cohort of these miRNA in additional samples to validate our microarray data. Comparing primary medulloblastoma cells to both adult and pediatric normal cerebellum revealed a significant down regulation of brain enriched microRNAs in medulloblastoma.There are four highly down regulated microRNAs namely, miR-125, miR-128a, miR -139 and let-7g.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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