Details
Disease Name Epilepsy, Temporal Lobe
Nocoding RNA Name hsa-miR-449b
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods TaqMan Array etc.
Target N/A
Tissue brain(hippocampus)
Treatment N/A
PubMed ID 25552301
Year 2015
Detail Description A total of 12 microRNA were found to be differentially expressed in temporal lobe epilepsy regardless of hippocampal sclerosis grade (miR-27b-5p, miR-129-2-3p, miR-129, miR-193a-5p, miR-362-3p and miR-520f upregulated; miR-218, miR-184, miR-449b, miR-34b, miR-34c and miR-548c downregulated).Finally, a panel of 13, methylation-sensitive microRNA were identified in temporal lobe epilepsy including MIR27A, miR-193a-5p (MIR193A) and miR-876-3p (MIR876), and the differential methylation of long non-coding RNA documented for the first time.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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