| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-451 |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | microarray,Luciferase Reporter Assay etc. |
| Target | SMAD4 |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 18765229 |
| Year | 2008 |
| Detail Description | microRNA microarrays for three out of six GBM tumors (p1, p2, and p4). The differentially expressed miRs in the CD133+ and CD133-fractions of a particular GBM sample (p1). Interestingly, the modulated miRs were not found to be overexpressed in the CD133+ cells, but rather several miRs were overexpressed in the CD133- fraction of all samples. These include hsa-miR-451, hsa-miR-486, hsa-miR-425,hsa-miR-16, hsa -miR-107, and hsa -miR-185. Similar results were obtained for the other two GBM samples.increased luciferase activity in the presence of SMAD3 or SMAD4, and when both activators were used, 6-fold luciferase inductions were observed. |
NSDNA: The Nervous System Disease NcRNAome Atlas
Contact wanglh211@163.com for inquiries and feedback
© All right reserved 2016