| Details |
| Disease Name | Stroke, Lacunar |
| Nocoding RNA Name | hsa-miR-487b |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | RT-PCR,Luciferase Reporter Assay etc. |
| Target | THBS1 |
| Tissue | plasma |
| Treatment | N/A |
| PubMed ID | 25660232 |
| Year | 2015 |
| Detail Description | miR-487b was up-regulated in the plasma of ischemic stroke patients. Further, over-expression of miR-487b enhanced cell proliferation, migration,invasion and tube formation in human umbilical vein endothelial cells. Using bioinformatic analysis, we found a putative binding site of miR-487b in the 3'untranslated regions of Thrombospondin 1 mRNA, an endogenous inhibitor of angiogenesis. This direct binding was confirmed by luciferase assay. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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