| Details |
| Disease Name | Meningioma |
| Nocoding RNA Name | hsa-miR-497 |
| Expression Pattern | differentially expressed |
| Species | Homo sapiens |
| Detection Methods | microarray, qRT-PCR etc. |
| Target | N/A |
| Tissue | brain(meningioma tissue) |
| Treatment | N/A |
| PubMed ID | 25681310 |
| Year | 2015 |
| Detail Description | We identified 13 miRNAs deregulated between different subtypes of benign meningiomas, and 52 miRNAs deregulated in anaplastic meningioma compared with benign meningiomas. Known and putative target genes of deregulated miRNAs include genes involved in epithelial-to-mesenchymal transition for benign meningiomas, and Wnt, transforming growth factor-b, and vascular endothelial growth factor signaling for higher-grade meningiomas. Furthermore, a 4-miRNA signature (miR-222, -34a*, -136, and -497) shows promise as a biomarker differentiating WHO grade II from grade I meningiomas with an area under the curve of 0.75. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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