| Details |
| Disease Name | Pituitary Neoplasms |
| Nocoding RNA Name | hsa-miR-516b |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | microarray,RT-PCR etc. |
| Target | N/A |
| Tissue | brain(pituitary tissues) |
| Treatment | bromocriptine |
| PubMed ID | 22366961 |
| Year | 2012 |
| Detail Description | The initial analysis of microRNA expression data generated a list of 71 microRNAs with a 1.2-fold lower expression in treated prolactinomas compared with untreated tumors, of which 6 microRNAs were downregulated in treated prolactinomas with a P-value <0.1. Inversely, the data also generated a list of 80 microRNAs, with 1.2-fold or higher expression in treated prolactinomas compared with untreated tumors, of which 9 microRNAs were upregulated in treated prolactinomas with a P-value <0.1.qRT-PCR expression analysis for relative expression of 3 specific microRNAs, miR-206, miR-516b and miR-550 were significantly higher in the treated prolactinomas compared to untreated prolactinomas. For another microRNA, miR-671-5p, the relative expression was significantly lower in treated prolactinomas. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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