| Details |
| Disease Name | Glioblastoma |
| Nocoding RNA Name | hsa-miR-517c |
| Expression Pattern | down-regulated |
| Species | Homo sapiens |
| Detection Methods | Real-time qPCR,Luciferase Reporter Assay,Western Blot etc. |
| Target | KPNA2 |
| Tissue | brain |
| Treatment | temozolomide |
| PubMed ID | 26553592 |
| Year | 2015 |
| Detail Description | MIR517C was associated with improved prognosis in patients with GBM. Furthermore, following treatment with the autophagy inducer temozolomide (TMZ) and low glucose (LG), MIR517C degraded KPNA2 (karyopherin alpha 2 [RAG cohort 1, importin alpha 1]) and subsequently disturbed the nuclear translocation of TP53 in the GBM cell line U87 in vitro. I. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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