| Disease Name |
Cerebral Amyloid Angiopathy, Familial |
| Nocoding RNA Name |
hsa-miR-582-3p |
| Expression Pattern |
mutated |
| Species |
Homo sapiens |
| Detection Methods |
Sanger sequencing,RT-QMPSF,RNA-binding protein immunoprecipitation etc. |
| Target |
APP |
| Tissue |
blood |
| Treatment |
N/A
|
| PubMed ID |
25828868 |
| Year |
2015 |
| Detail Description |
We sequenced the 3’UTR of APP in 90 patients, we identified three sequence variants in four patients.miR-892b significantly downregulated APP expression, whereas the ΔTA variant blocked this effect. Interestingly, miR-582-3p caused an increase in APP expression only in the presence of the ΔTA variant. |
|