Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-622
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods RT-PCR,Western Blot,Luciferase Reporter Assay etc.
Target K-Ras
Tissue brain
Treatment N/A
PubMed ID 26596833
Year 2015
Detail Description We demonstrated that miR-622 expression was lower in tumor tissues and cells, when compared to normal brain tissues and normal human astrocyte (NHA) cells, while K-Ras messenger RNA (mRNA) and protein showed the opposite expression profile. we discovered that wild Kirsten rat sarcoma (K-Ras) was a direct target of miR-622, which decreased the expression of K-Ras protein in A172, U87, and U251 cells.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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