Details
Disease Name Growth Hormone-Secreting Pituitary Adenoma
Nocoding RNA Name hsa-miR-636
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods miRNACHIP microarray etc.
Target N/A
Tissue brain(pituitary tissues)
Treatment N/A
PubMed ID 22564666
Year 2012
Detail Description We report the identification of a set of miRNA, including miR-34b, miR-326, miR-432, miR-548c-3p, miR-570, and miR-603, drastically and constantly down-regulated in GH adenomas.We demonstrate that these miRNA target genes such as high-mobility group A1 (HMGA1),HMGA2, and E2F1, whose overexpression and/or activation plays a critical role in pituitary tumorigenesis.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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